| 张远东,张 卓,董紫薇,阚君满.化学通报,2023,86(2):173-178. |
| 纳米材料在肿瘤光动力治疗中的研究进展 |
| Progress in Nanomaterials for Tumor Photodynamic Therapy |
| 投稿时间：2022-07-05 修订日期：2022-09-04 |
| DOI： |
| 中文关键词: 光动力治疗 纳米材料 肿瘤 |
| 英文关键词:photodynamic therapy, nanomaterials, tumor |
| 基金项目:吉林省教育厅项目(JJKH20220210KJ)和吉林工商学院科研项目(KB2021[003])资助 |
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| 中文摘要: |
| 光动力治疗是新兴的非侵入性癌症治疗方法。纳米材料以其独特的结构以及光物理、光化学性质成为可用于光动力治疗的光敏剂。根据纳米材料的不同种类,分别对无机非金属纳米材料、无机金属纳米材料、有机小分子纳米材料以及有机聚合物纳米材料等的构建策略及其在光动力治疗肿瘤中的应用进行综述。展望了纳米材料在未来肿瘤光动力治疗中的挑战和发展方向。为新一代纳米光敏剂的构建提供创新思路,并扩展其在癌症治疗中的潜力。 |
| 英文摘要: |
| Photodynamic therapy has emerged as an innovative non-invasive treatment for cancer. Nanomaterialswith distinctive structure, photophysical and photochemical properties have been utilized as photosensitizer forphotodynamic therapy of tumors. The construction strategies of nanomaterials and their applications in photodynamictherapy are reviewed according to the different categories of nanomaterials, such as inorganic non-metallicnanomaterials, inorganic metallic nanomaterials, organic small molecule nanomaterials, and organic polymericnanomaterials. The future challenges and development directions of the nanomaterials in photodynamic therapy areprospected. It is expected that this paper will provide innovative ideas for constructing a new generation ofnanophotosensitizers and expand their potential applications in cancer treatment. |
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