| 茆勇军,何海军.化学通报,2014,77(10):950. |
| 4-羟基喹啉类化合物的合成研究进展 |
| Progress in Synthesis of 4-Hydroxyquinoline Derivatives |
| 投稿时间：2014-03-09 修订日期：2014-03-28 |
| DOI： |
| 中文关键词: 4-羟基喹啉类化合物 合成方法 |
| 英文关键词:4-hydroxyquinoline, synthesis, progress |
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| 中文摘要: |
| 4-羟基喹啉类[4-hydroxyquinoline或4(1H)quinolone]化合物是一类重要的药物合成中间体,在抗疟、抗癌、抗菌、抗病毒、抗糖尿病等领域发挥重要作用。本文综述了4-羟基喹啉类结构的合成方法,包括热环合、碱环合和还原环合等。 |
| 英文摘要: |
| 4-Hydroxyquinoline [or 4 (1H) quinolone] derivatives are important intermediates in pharmaceutical synthesis and play significant roles in antimalarial, anticancer, antibacterial, antiviral and antidiabetic. Progress in synthesis of 4-hydroxyquinoline derivatives, including thermal, basic and reductive cyclization methods, are summarized in this review. |
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