| 刘玮炜,李曲祥,程峰昌,张强,霍云峰.化学通报,2014,77(11):1064-1075. |
| D-氨基葡萄糖N-位和苷羟基化学改性的研究进展 |
| Progress in Chemical Modification of D-glucosamine N-site and Glycoside Hydroxy |
| 投稿时间：2014-03-17 修订日期：2014-05-05 |
| DOI： |
| 中文关键词: D-氨基葡萄糖 化学改性 方法 |
| 英文关键词:D-Glucosamine, Chemical modification, Approach |
| 基金项目:江苏省高校自然科学研究重大项目（10KJA170003）资助；江苏省高校科研成果产业化推进项目(No. JHB2012-60)资助；连云港市科技攻关项目(CG1105)及江苏高校优势学科建设工程资助项目资助. |
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| 中文摘要: |
| D-氨基葡萄糖是甲壳素的最终水解产物,它作为一种天然的氨基单糖,广泛存在于各种生物体内。D-氨基葡萄糖分子含有一个氨基和四个羟基,由于其结构的特殊性,对其进行研究具有重要意义。目前,D-氨基葡萄糖及其衍生物研究备受科学家青睐,其产品已应用于诸多领域,如生物和医药等。为此,本文综述了近年来对氨基葡萄糖N-位和苷羟基进行化学改性的研究进展,着重介绍了选择性化学修饰的方法和发展动向。 |
| 英文摘要: |
| D-Glucosamine as a natural amino monosaccharide widely exists in a variety of organisms, which is the final degradation product of chitin. The molecule contains one amido and four hydroxyls. It is of great significance to research on it due to the special nature of its structure. Currently, D-Glucosamine and its derivatives are paied more attention to by scientists, and its products have been applied in many fields, such as biology, medicine and so on. Therefore, the review has a closer look at chemical modification of D-Glucosamine N-site and glycoside hydroxy. The methods of selective chemical modification of D-glucosamine are especially introduced. |
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