康 祺,于炜婷,吴 叶,刘袖洞,马小军.化学通报,2015,78(3):236.
非共价键交联海藻酸钠水凝胶的制备与性能
Preparation and property of sodium alginate hydrogel cross-linked by non-covalent bonds
投稿时间:2014-11-10  修订日期:2014-12-11
DOI:
中文关键词:  海藻酸钠  水凝胶  非共价键交联
英文关键词:Sodium alginate  Hydrogel  Non-covalent bonds
基金项目:国家自然科学基金项目(21276033)和辽宁省“十百千高端人才引进工程”启动基金(人社[2012]207号)资助
作者单位E-mail
康 祺 大连大学环境与化学工程学院 540960459@qq.com 
于炜婷 中国科学院大连化学物理研究所  
吴 叶 大连大学环化学院  
刘袖洞 大连大学 liuxd@dicp.ac.cn 
马小军 中国科学院大连化学物理研究所  
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中文摘要:
      天然多糖海藻酸钠制备的水凝胶具有优越的生物相容性和生物组织相似性,作为生物医用材料在药物控制释放、组织工程支架、抗菌材料及创伤敷料等领域发挥着越来越大的作用。本文在介绍海藻酸钠物化性质的基础上,重点综述了非共价键交联(静电作用、氢键、范德华力、亲疏水作用等)海藻酸钠水凝胶的制备方法以及性能表征方法,最后讨论了制备方法及性能表征研究中的一些需要解决的问题。
英文摘要:
      Sodium alginate hydrogel has been widely used as biomedical materials in drug delivery system, tissue engineering scaffolds, antibacterial material and wound dressing, due to their superior biocompatibility and resemblance to biological tissues. Based on the brief introduction of physicochemical properties of sodium alginate, the progress of preparation methods of sodium alginate hydrogel cross-linked by non-covalent bonds is summarized including electrostatic interaction, hydrogen bonds, van der Waals forces and hydrophobic effects, etc. Meantime, the characterization methods on properties of sodium alginate hydrogel are also concerned. Finally, some problems related to the development of preparation and characterization methods are discussed.
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