| 孟凡斌,徐 慧,兰 伟,刘冲冲,纪秀翠.化学通报,2015,78(6):489-496. |
| 水溶液中金属增强荧光的研究进展 |
| The Research Progress on Metal Enhanced Fluorescence in Aqueous Solution |
| 投稿时间：2014-12-03 修订日期：2015-01-21 |
| DOI： |
| 中文关键词: 金属增强荧光 Ag@SiO2纳米粒子 生物检测 |
| 英文关键词:Metal enhanced fluorescence,Ag@SiO2 nanoparticles, Biological detection |
| 基金项目:国家自然科学基金(21104030) 山东省自然科学基金重点项目(ZR2013EMZ001) 山东省自然科学基金(ZR2013CM018，ZR2011BQ012) 烟台市科技发展计划项目(项目编号：2013NC049)。 |
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| 中文摘要: |
| 本文综述了水溶液中金属增强荧光的研究进展，重点阐明如何通过控制荧光物质与金属纳米粒子表面的距离，实现水溶液中的金属增强荧光。荧光物质与金属纳米粒子表面的距离主要通过有机分子和无机分子层SiO2控制，只有当距离合适才能达到最大的金属增强荧光。金属增强荧光提高了荧光检测的灵敏度，扩大了荧光技术的应用范围，已广泛应用到DNA、蛋白质检测，生物标记，生物成像和免疫分析中。 |
| 英文摘要: |
| The research progress on metal enhanced fluorescence in aqueous solution was reviewed in this paper. We will focus on how to control the distance between fluorescent material and the surface of the metal nanoparticles in aqueous solution to realize the metal enhanced fluorescence. The distance between fluorescent material and the surface of the metal nanoparticles is mainly controlled by organic molecules and inorganic molecular layer of SiO2 and only the appropriate distance can lead to the largest metal enhanced fluorescence. Metal enhanced fluorescence enhances the sensitivity of the fluorescence detection and enlarges the range of the fluorescence technique, which has been widely used for application of DNA or protein detection, biological labeling, biological imaging and immune analysis. |
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