谢宗波,孙大召,陈中胜,乐长高.化学通报,2015,78(8):757-760. |
NaBF4催化合成二吲哚甲烷类化合物 |
Synthesis of Bis(indolyl)alkanes Catalyzed by Sodium Fluoroborate |
投稿时间:2015-02-10 修订日期:2015-03-17 |
DOI: |
中文关键词: NaBF4 乙醇水溶液 二吲哚甲烷 串联反应 |
英文关键词:NaBF4 ethanol aqueous solution bis(indolyl)alkane cascade reaction |
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中文摘要: |
在乙醇水溶液中,以NaBF4为催化剂,通过吲哚与芳香醛间的串联反应,合成了一系列二吲哚甲烷衍生物。考察了催化剂种类、反应介质、温度、反应时间等因素对反应的影响,在最优条件下得到了一系列产率较高的目标产物。 |
英文摘要: |
A cascade reaction catalyzed by NaBF4 was firstly reported for the synthesis of bis(indolyl)methanes starting from indole and aromatic aldehydes in ethanol aqueous solution. The reaction conditions was optimized with catalyst, medium, temperature and reaction time, and a series of bis(indolyl)alkanes were obtained in moderate to good yields under the optimal reaction conditions. |
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