| 聂立波,肖湘云,杨鸿成.化学通报,2015,78(8):727. |
| 金纳米簇的制备及其在生物医学中的应用 |
| Preparation and Biomedical Applications of Gold Nanoclusters |
| 投稿时间：2015-04-15 修订日期：2015-05-14 |
| DOI： |
| 中文关键词: 金纳米簇 荧光 生物检测 荧光成像 药物控释 |
| 英文关键词:Gold nanoclusters Fluorescence Bioanalysis Fluorescence imaging Controlled drug delivery |
| 基金项目: |
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| 中文摘要: |
| 金纳米簇由几个到几十个金原子组成，具有尺寸小、荧光性能好、无毒等优点，被广泛应用于生物医学领域。本文介绍了包括模板法，刻蚀法，可逆相转移法和动力学控制法等金纳米簇的主要制备方法，并综述了金纳米簇在生物医学上的主要应用，包括生物检测、荧光成像和药物控释。 |
| 英文摘要: |
| Gold nanoclusters (Au NCs) consist of several or dozens of gold atoms. Due to small size, strong fluorescence emission and non-toxic properties, Au NCs are widely used in the field of biomedicine. Herein the preparation methods of Au NCs including template method, etching method, reversible phase-transfer method and dynamics controlling method and their biomedical applications including bioanalysis, fluorescence imaging and controlled drug delivery are reviewed. |
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