梁泳,汪翔,周孝湖,李家琦,徐 海.化学通报,2016,79(8):719-722. |
芳香低聚酰胺类α-螺旋模拟物研究进展 |
Research development of α-helix mimetics based on aromatic oligoamides |
投稿时间:2015-12-17 修订日期:2016-04-22 |
DOI: |
中文关键词: 芳香低聚酰胺 α-螺旋 模拟物 抑制剂 蛋白质-蛋白质相互作用 |
英文关键词:aromatic oligoamides α-helix mimetic inhibitor protein-protein interaction |
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中文摘要: |
α-螺旋模拟物是一类重要的小分子蛋白质相互作用抑制剂。芳香低聚酰胺类小分子α-螺旋模拟物具有许多优点,近年来取得了较快的发展。综述了近几年来芳香低聚酰胺类α-螺旋模拟物的最新进展。 |
英文摘要: |
α-helix mimetics are an important class of small molecule inhibitors of protein-protein interactions. Small molecular α-helix mimetics which are derived from aromatic oligoamides have many advantages and achieved rapid development in recent years. The latest progress of α-helix mimetics based on aromatic oligoamides was reviewed. |
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