| 尤文钰,杨铁金.化学通报,2016,79(11):1035-1040. |
| 纳米银/石墨烯修饰电极测定青蒿素 |
| A Glassy Carbon Electrode Modified with Graphene and Silver Nanoparticles for Determination of Artemisinin |
| 投稿时间：2016-03-11 修订日期：2016-04-20 |
| DOI： |
| 中文关键词: 青蒿素 石墨烯 纳米银 修饰电极 |
| 英文关键词:Artemisinin, Graphene, Ag nanopaticles, modified electrode |
| 基金项目: |
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| 摘要点击次数: 2380 |
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| 中文摘要: |
| 本文建立一种新型的青蒿素传感器，首先，在玻碳电极上滴涂氧化石墨烯通过电化学方法将氧化石墨烯还原为石墨烯，然后，在石墨烯上沉积纳米银得到石墨烯/纳米银修饰电极，它作为检测青蒿素的电化学传感器。用此电极对青蒿素进行测定并通过循环伏安法、差分脉冲伏安法、交流阻抗法等研究其电化学行为。该修饰电极在测定青蒿素溶液时，表现出较正的还原电位和较大的峰电流等优势，并对其实验条件如电解质溶液的pH、应用电势等进行了探查，该电化学传感器在青蒿素溶液浓度为1.1×10-8～3.0×10-6与其还原峰电流呈现良好的线性关系，最低检出限为1.2×10-9（S/N=3）。此外，对该传感器的稳定性和重现性等也进行了研究，获得的结果令人满意。 |
| 英文摘要: |
| In this work, a novel artemisinin sensor was developed. Graphene oxide was coated and reduced to graphene (GN) on a glassy carbon electrode (GCE) by electrochemical method. Then, Ag nanoparticles were deposited on the above electrode to fabricate silver nanopaticles/graphene modified electrode(AgNPs/GN/GCE), it was denoted as the electrochemical sensor of artemisinin . The electrochemical behaviour of the modified electrode was studied by cyclic voltammetry, differential pulse voltammetry, electrochemical impedance spectroscopy, and so on. The modified electrode displays excellent performance in the electrochemical reduction of artemisinin in showing more positive reduction peak potential and high reduction peak currents. The effects of the experimental variables on the determination of arteminin such as solution pH and applied potential were investigated for optimum analytical conditions, the electrochemical sensor exhibited linear response to artemisinin in the concentration ranges from 1.1×10-8 to 3.0×10-6 mol/L, with a detection limit of 1.2×10-9 mol/L (S/N of 3). In addition, the stability and reproducibility of this sensor was also evaluated and gave satisfactory results. |
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