王欢,商珞然,戎非,顾忠泽,赵远锦.化学通报,2017,80(3):219-227.
胶体晶体微球及其生物医学应用
Colloidal Crystal Beads with Biomedical Applications
投稿时间:2016-10-16  修订日期:2016-11-14
DOI:
中文关键词:  胶体晶体 微球 微流控 生物材料 生物医学工程
英文关键词:Colloidal crystal, Microbeads, Microfluidics, Biomaterials, Biomedical engineering
基金项目:国家自然科学基金项目(21473029,51522302)、NSAF联合基金项目(U1530260)和江苏省杰出青年基金(BK20140028)资助
作者单位E-mail
王欢 
东南大学生物电子学国家重点实验室 南京 210096 
wang_huan@seu.edu.cn 
商珞然 
东南大学生物电子学国家重点实验室 南京 210096 
 
戎非 
东南大学生物电子学国家重点实验室 南京 210096 
 
顾忠泽 
东南大学生物电子学国家重点实验室 南京 210096 
 
赵远锦* 
东南大学生物电子学国家重点实验室 南京 210096 
yjzhao@seu.edu.cn 
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中文摘要:
      光子晶体(PhCs)是由单分散纳米粒子周期性排列形成的材料,具有光子禁带(PBGs),频率落在光子禁带内的光被禁止传播,这个特性激起了研究者对其制备和应用的研究热情。然而一般的光子晶体材料都具有角度有偏性质,限制了其在宽视角光学材料和设备上的应用。近几年有一系列围绕球形胶体光子晶体材料的研究成果问世,由于球形的对称性,球形胶体晶体的衍射峰不会随着光的入射角变化而发生变化,这拓宽了胶体晶体的应用范围。随着微流控技术被用于制备液滴模板,球形胶体晶体的制备取得了巨大的进步。微流控技术不仅保证了液滴模板的单分散性,还增加了胶体晶体微球的结构与功能的多样性。胶体晶体微球这些特有的性质,可以很好地将光子晶体材料与编码、非标记检测、细胞培养以及载药等生物医学领域连接起来,为其应用提供了广阔的前景。在这篇综述中,我们总结了球形光子晶体的研究进展,包括球形光子晶体的设计、制备及其生物医学应用。最后,我们对球形光子晶体未来的发展做了一些展望。
英文摘要:
      Colloidal photonic crystals (PhCs) were periodically arranged monodisperse nanoparticles and have photonic band gaps (PBGs), and the light with certain wavelengths or frequencies located in the PBG being prohibited from propagating. Because of this special property, the fabrication and application of colloidal PhCs have attracted increasing interest from researchers. However, the angle dependence is disadvantageous for the construction of some optical materials and devices in which wide viewing angles are desired. Recently, a series of colloidal PhC materials with spherical macroscopic morphology have been created. Because of their spherical symmetry, the PBGs of spherical colloidal PhCs are independent of rotation under illumination of the surface at a fixed incident angle of the light, broadening the perspective of their applications. Because microfluidics was used for the generation of the droplet templates, the development of spherical colloidal PhCs has progressed significantly. These new strategies not only ensure monodispersity, but also increase the structural and functional diversity of the PhC beads (PCBs). These novel PCBs provide a bridge between PhCs materials and biomedical applications such as barcodes, label-free detection, cell culture and drug delivery, and this also leads PCBs to far-ranging real-world applications. In this review, we present the research progress on PCBs, including their design, preparation, and potential applications. Future developments of the PCB materials are also envisioned.
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