| 肖彩琴.化学通报,2017,80(10):908-917. |
| 砜类化合物合成研究进展 |
| Progress on the Synthesis of Sulfones |
| 投稿时间：2017-01-25 修订日期：2017-06-08 |
| DOI： |
| 中文关键词: 砜类化合物 合成 研究进展 |
| 英文关键词:Sulfones, Synthesis, Research progress |
| 基金项目: |
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| 中文摘要: |
| 砜类化合物具有广谱的生物活性，广泛应用于化学、医药、农药、材料科学等领域。同时，作为强吸电子基团，砜类化合物可以通过碱和亲电试剂反应延长碳链，因此该类化合物合成方法引起了国内外研究人员的高度重视，本文结合国内外学者对这方面的相关研究，重点从硫醚氧化、磺酰氯的磺酰化和亚磺酸盐的偶联三个方面对近几年来砜类化合物合成方法进行了综述。 |
| 英文摘要: |
| The broad spectrum of biological activity of sulfone compounds endows a wide applications in chemistry, medicine, agrochemistry and material science. Being an strong electron-withdrawing group, elongation of carbon chain could easily achieved via reaction of aliphatic sulfones with various electrophiles under basic condition. As a result, novel synthetic methodologies have continuous been developed especially during the past decades. This paper aimed at summarizing the synthetic methods of the sulfone compounds appeared in recent years, emphasizing the oxidation of sulfides, sulfonylation with sulfonyl chlorides and coupling of sulfinic acid salts. |
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