| 丁旭光,于海丰,赵辉,杨勇.化学通报,2017,80(12):1152-1155. |
| a-二芳甲基-b-羰基硫代羧酸酯与肼的环合反应：官能化含5-羟基吡唑基的三芳基甲烷类化合物的合成 |
| Cyclization of a-Diaryl methyl-b-oxothioesters and hydrazine: Synthesis of Functionalized 5-Hydroxy Pyrazolyl-ContainingTriarylmethanes |
| 投稿时间：2017-05-30 修订日期：2017-08-20 |
| DOI： |
| 中文关键词: 硫代羧酸酯 三芳基甲烷 环合反应 5-羟基吡唑 |
| 英文关键词:thioester, triarylmethane, cyclization reaction, 5-hydroxy pyrazole |
| 基金项目:辽宁省自然基金项目(201602002),吉林省有机功能分子设计与合成重点实验室开放基金(130028652)和辽宁省教育厅项目(L2015003)资助。 |
|
| 摘要点击次数: 2210 |
| 全文下载次数: 0 |
| 中文摘要: |
| 本文研究了合成官能化含5-羟基吡唑基的三芳基甲烷类化合物的a-二芳甲基-b-羰基硫代羧酸酯与肼的环合反应。研究表明,在乙醇介质中,回流条件下, a-二芳甲基-b-羰基硫代羧酸酯与肼能有效进行环合反应,高产率制得5-羟基吡唑基三芳甲烷类化合物。该反应条件温和,产率高,操作简单。 |
| 英文摘要: |
| We developed the cyclization reactions of ?-diaryl methyl-?-ketothioesters and hydrazine for the synthesis of functionalized 5-hydroxy pyrazolyl-containing triarylmethanes. Our studies had shown that the cyclization reactions of ?-diaryl methyl-?-ketothioesters and hydrazine smoothly performed in refluxing EtOH, affording functionalized 5-hydroxy pyrazolyl-containing triarylmethanes in excellent yield. Mild reaction conditions,easy work-up procedure, and excellent yields are some notable advantages of our work. |
| 查看全文 查看/发表评论 下载PDF阅读器 |
| 关闭 |