| 吕菊波,纪秀翠,张亚会,徐慧.化学通报,2018,81(3):195-202. |
| 聚-N-异丙基丙烯酰胺的制备及应用进展 |
| Progress in Preparation and Application of Poly(N-isopropylacrylamide) |
| 投稿时间：2017-09-20 修订日期：2017-12-03 |
| DOI： |
| 中文关键词: 聚(N-异丙基丙烯酰胺),温敏性,最低临界溶解温度 |
| 英文关键词:Poly(N-isopropylacrylamide), Thermally responsive, Lower critical solution temperature |
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| 中文摘要: |
| 聚(N-异丙基丙烯酰胺)又称PNIPAM,是一种温敏性的高分子聚合物,对温度具有很好的刺激响应性。在最低临界溶解温度(LCST)处会发生构象转变。加以改性,可拓宽温敏性聚合物材料的研究领域,使其在药物负载运输,基因传递,化学分析等领域里发挥更大的应用价值。本文对PNIPAM的活性自由基聚合方法及其应用进展进行了综述,并展望了其发展前景。 |
| 英文摘要: |
| Poly(N-isopropylacrylamide) (PNIPAM) is one of the thermally responsive polymers, which has a lower critical solution temperature (LCST), and there is a phemomenon of the conformation variation around this temperature. The modification of PNIPAM play an important role in so many areas, such as the drug delibery, gene transfer and biochemical analysis and so on. In this article, the reaesrch progress of preparation and application of PNIPAM, and the prospects of this field were also put forward. |
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