| 刘世钊,阿布都热西提·阿布力克木.化学通报,2019,82(3):270-274. |
| 一种简单、温和、高效、无金属催化的双硫化物合成方法 |
| A simple, mild, efficient and metal-free synthesis method of disulfides |
| 投稿时间：2018-10-15 修订日期：2018-11-21 |
| DOI： |
| 中文关键词: 双硫化合物 α, α, α-三溴苯乙酮 自由基反应 |
| 英文关键词:disulfides α, α, α-three bromoacetophenone Free radical reaction metal-free |
| 基金项目: |
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| 摘要点击次数: 1990 |
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| 中文摘要: |
| 本文通过95%乙醇作为溶剂,在三溴苯乙酮的存在下与硫酚或硫醇发生自身偶联反应生成双硫化合物。这是继传统方法之后一种温和、操作简单、绿色并且无金属催化的合成方法。在最优化反应条件下考察了多种苯硫酚和硫醇类化合物,发现芳环供电基团比芳环吸电子基团能获得更高的产率,并且反应时间较吸电基团相比也有所减少；同时底物为脂肪族和杂环类化合物也有较高的产率。 |
| 英文摘要: |
| In this paper, 95% ethanol was used as solvent to form disulfide compounds by coupling with Thiophenol or mercaptan in the presence of tribromophenone. This is a mild, simple, green and metal-free synthesis method following the traditional method. A variety of thiophenols and mercaptans were investigated under the optimum reaction conditions. It was found that the aromatic ring-supported group could obtain higher yields than the aromatic ring-supported group, and the reaction time was shorter than that of the charged group. At the same time, the substrates of aliphatic and heterocyclic compounds also had higher yields. |
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