| 钱晨,钱颖,崔司琪,王晶晶.化学通报,2019,82(5):399-403. |
| 富勒烯/环糊精复合物及其在生物医药领域应用的研究进展 |
| Fullerene/cyclodextrin composite materials and the application in biomedicine |
| 投稿时间：2018-11-20 修订日期：2019-01-04 |
| DOI： |
| 中文关键词: 富勒烯,环糊精,包合,共价偶联，富勒烯/环糊精复合物 |
| 英文关键词:Fullerene, Cyclodextrin, Inclusionsystem, Covalent coupling system, fullerene/cyclodextrin composite materials |
| 基金项目:江苏高校优势学科建设工程项目 (PAPD) |
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| 摘要点击次数: 2014 |
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| 中文摘要: |
| 富勒烯有着独特的球形结构，这一结构赋予了其优异的光电及生物性能，在生物医药领域备受关注。环糊精具有良好的水溶性和生物相容性，锥筒状结构赋予了其特异性包合作用，在主客体化学中有着非常重要的地位。富勒烯/环糊精的复合物，结合了富勒烯和环糊精的优势，在DNA切割，光动力学疗法，药物载体等领域发挥了重要作用。本文从富勒烯与环糊精体系的构筑出发，综述了富勒烯/环糊精非共价包合物及共价偶联物在生物医药领域应用的研究进展，且对富勒烯/环糊精复合物的应用进行了展望，为构建新型富勒烯/环糊精复合物提供参考。 |
| 英文摘要: |
| Fullerene, a spherical carbon allotrope, with excellent photoelectric and biological properties has attracted special attention in the field of biomedicine. Cyclodextrin, a cone-shaped cyclic oligosaccharide, with well-solubility, good biocompatibility and specific inclusion property plays an important role in host-guest chemistry. The fullerene/cyclodextrin composite materials, which combine the advantages of fullerene and cyclodextrin, play an important part in DNA cleavage, photodynamic therapy, drug carriers and other biomedicine fields. Based on the construction of fullerene/cyclodextrin systems, the research progress of non-covalent and covalent composite materials of fullerene/cyclodextrin were reviewed and the application of fullerene/cyclodextrin composite materials is prospected. It provides a reference for the construction of new fullerene/cyclodextrin composite materials. |
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