| 薛鹏仙,龙泽荣.化学通报,2019,82(7):598-605,597. |
| 硫熏中药材品质及其毒理学研究进展 |
| Advances in quality and toxicology study of Sulfur-fumigated Chinese medicine materials |
| 投稿时间：2019-03-14 修订日期：2019-04-12 |
| DOI： |
| 中文关键词: 硫熏 中药材 硫的形态 含硫衍生物 毒理学 |
| 英文关键词:Sulfur fumigation Chinese herbal medicine morphology of sulfur element sulfur-containing derivatives toxicology |
| 基金项目:天山青年计划（2017Q063）资助 |
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| 中文摘要: |
| 硫磺熏蒸是我国传统中药材干燥的一种加工方法，该方法具有杀虫、防霉、防腐和增白等功效。近年来，研究发现硫磺熏蒸会导致中药材某些活性成分转化生成新的含硫衍生物，导致其在人体的代谢过程和药效发生改变，甚至引发毒性反应，存在安全隐患。本文在现有文献的基础上归纳总结硫元素的各种形态、硫磺熏蒸中药材化学成分的转化规律及其毒理学研究，为进一步评价硫熏工艺的合理性研究提供理论参考。 |
| 英文摘要: |
| Sulfur fumigation, is a traditional drying method to prevent Chinese medicine materials from insects, molds and erosion etc, and can be used to bleach them. In recent years, investigations have found that the certain active components of traditional Chinese medicine (TCM) can be transformed into sulfur-containing derivatives in the process of sulfur fumigation, resulting in changes in metabolism and pharmacodynamics in the body, and even production of toxic reactions. This paper summarizes comprehensively the various morphologies of sulfur elements, chemical transformation rules of TCM and the toxicological studies in sulfur- fumigation. The review would provide the valuable references for further evaluating the rationality of sulfur fumigation process of TCM . |
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