谭新刚,施小新.化学通报,2022,85(6):755-758.
育亨宾类似物Sempervilam的全合成
The total synthesis of yohimbane analogue Sempervilam
投稿时间:2021-08-31  修订日期:2021-09-30
DOI:
中文关键词:  育亨宾类似物  合成
英文关键词:yohimbane analogue  Sempervilam  synthesis
基金项目:
作者单位E-mail
谭新刚 华东理工大学 txgecust@163.com 
施小新* 华东理工大学 药学院 xxshi@ecust.edu.cn 
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中文摘要:
      以庚二酸为起始原料,经过十步反应,得到目标产物Sempervilam,总收率19%。其结构经1H NMR,13C NMR,IR和MS表征。此法绿色环保、成本较低,适合工业化生产。
英文摘要:
      The desired compound Sempervilam was prepared from heptanediacid. The total yield of the ten steps is 19%.The structures of all compounds were characterized by 1H NMR, 13C NMR, IR and MS. The method is environmentally friendly, lower cost, and suitable for industrial production.
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