周鸿,鲁琴芮,李毅,周春阳,罗荧萍.化学通报,2022,85(11):1304-1311,1296.
基于纳米金的ATP检测体系的研究进展
Gold Nanoparticles-based Sensor for ATP Detection
投稿时间:2022-02-19  修订日期:2022-04-06
DOI:
中文关键词:  ATP  纳米金  检测探针  评述
英文关键词:ATP, Gold  nanoparticles, Detection  probe, Review
基金项目:2021年中央引导地方科技发展资金面上项目(2021ZYD0051)、川北医学院博士科研启动项目(CBY19-QD03)和2020川北医学院药学一流学科群建设项目(CBY20-YLXK03)资助
作者单位E-mail
周鸿 川北医学院 南充 637000 2577434323@qq.com 
鲁琴芮 川北医学院 南充 637000  
李毅 川北医学院 南充 637000  
周春阳 川北医学院 南充 637000  
罗荧萍 川北医学院 南充 637000 lyingping@163.com 
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中文摘要:
      ATP是机体代谢过程中不可或缺的能量物质,参与机体的各项重要的生理生化活动,在各方面起着至关重要的作用。因此,对ATP的快速精准检测具有重要的临床意义。纳米金(AuNPs)因优良的光学特性、催化活性、生物相容性等特点,被广泛应用于构建ATP检测体系。本文综述了目前AuNPs应用于ATP检测的研究进展,如比色检测、荧光分析、电化学检测、电化学发光检测、化学发光检测以及表面增强拉曼散射等,比较了各种检测方法的优点与不足,并对AuNPs在ATP检测应用中面临的挑战和机遇做了展望。
英文摘要:
      ATP is an indispensable energy substance in the body"s metabolic process. It participates in various important physiological and biochemical activities and plays a vital role in various aspects. Therefore, the rapid and accurate detection of ATP has important clinical significance. Gold nanoparticles (AuNPs) are widely used to construct ATP detection sensors due to their excellent optical properties, catalytic activity, and biocompatibility. In this paper, advantages and deficiencies of ATP sensors based on AuNPs, such as colorimetric, fluorescence, electrochemical, chemiluminescence, electrochemiluminescence and surface-enhanced Raman scattering analysis, were summarized. Mover, the challenges and opportunities of AuNPs application in ATP detection were discussed.
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