余栅删,唐丽娜,李玉桃.化学通报,2023,86(4):429-436.
用于褪黑素检测的电化学生物传感器研究进展
Advances of electrochemical biosensors for melatonin detection
投稿时间:2022-07-15  修订日期:2022-08-22
DOI:
中文关键词:  褪黑素  电化学  传感器  伏安法
英文关键词:melatonin  electrochemistry  sensor  voltammetry
基金项目:国家自然科学基金项目(21974036)资助
作者单位E-mail
余栅删* 湖北中医药大学检验学院 813561026@qq.com 
唐丽娜 湖北中医药大学检验学院  
李玉桃 湖北中医药大学检验学院  
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中文摘要:
      褪黑素是人体松果体分泌的一种重要的神经递质,近年来其在控制昼夜节律和提供免疫抗炎特性等生理调节作用方面备受关注。因此,发展可靠、快速检测体内和体外样本中褪黑素浓度的方法,对于探索褪黑素的临床应用和生物学特性具有重要的意义。本文对褪黑素的基本概述、褪黑素的传统检测方法进行简要介绍,重点阐述了近几年报道的用于生物样本和药物样本中褪黑素定量检测的电化学传感器,并对褪黑素传感器的未来发展方向做出展望。
英文摘要:
      Melatonin is an important neurotransmitter secreted by the human pineal gland. In recent years it has received much attention for its physiological regulatory role in controlling circadian rhythms and providing immune anti-inflammatory properties. Therefore, the development of reliable and rapid methods for the detection of melatonin concentration in vivo and in vitro is of great significance for exploring the clinical application and biological characteristics of melatonin. In this paper, we give a brief overview of melatonin and traditional methods for melatonin detection. We also highlight the electrochemical sensors reported in recent years for the quantitative detection of melatonin in biological and pharmaceutical samples and provide an outlook on the future direction of melatonin sensors.
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