| 张劲,汪宜宇,金政,赵凯.化学通报,2025,88(1):48-55. |
| 聚合物水凝胶在生物医药载体方面的研究应用进展 |
| Advances in the Research and Application of Polymeric Hydrogels in Biomedical Carriers |
| 投稿时间：2024-09-06 修订日期：2024-10-11 |
| DOI： |
| 中文关键词: 聚合物水凝胶 生物医药 递送载体 生物相容性 |
| 英文关键词:Polymer hydrogel, Biomedicine, Delivery carrier, Biocompatibility |
| 基金项目:国家自然科学基金面上项目(32170844)、浙江省自然科学基金联合项目(LTY22E030002)和台州市科技计划项目(22gyb02)资助 |
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| 中文摘要: |
| 聚合物水凝胶是具有三维结构的仿生交联聚合物网络,含水量高且高度多孔,不仅具有良好的生物可降解性和生物相容性,而且可以通过修饰其官能团或掺入天然聚合物来调节其功能,在递送载体领域得到广泛研究应用。本文综述了聚合物水凝胶的分类、制备方法和应用,介绍了一些已上市的生物医药载体聚合物水凝胶产品并分析了聚合物水凝胶在生物医药载体方面的研究进展、面临问题和研究建议,为该领域的研究人员提供参考。 |
| 英文摘要: |
| Polymer hydrogels are biomimetic, three-dimensional, high water content, highly porous polymer networks. Polymer hydrogels have been widely researched and applied in the field of delivery carriers due to their good biodegradability and biocompatibility, and even the ability to modulate the delivery function by modifying their functional groups or incorporating natural polymers. This paper reviews the classification, preparation methods and applications of polymer hydrogels, introduces some marketed polymer hydrogel products for biopharmaceutical carriers and analyses the research progress, problems and research suggestions of polymer hydrogels in biopharmaceutical carriers, which provide references for researchers in this field. |
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