| 赵晨彤,陈静怡,张伟娜,翟宏菊,原景玲,刘姝彤.化学通报,2025,88(4):354-368. |
| 纳米级药物载体的制备及其抗癌、抗菌应用新进展 |
| Recent Advances in the Preparation of Nanoscale Drug Carriersand their Applications in Anticancer and Antimicrobial Therapies |
| 投稿时间：2024-12-17 修订日期：2025-02-06 |
| DOI： |
| 中文关键词: 药物递送 脂质体 纳米颗粒 碳纳米材料 |
| 英文关键词:Drug Delivery Liposomes Nanoparticles Carbon Nanomaterials |
| 基金项目:吉林省科技发展计划项目(YDZJ202401375ZYTS)、吉林省发展和改革委员会项目(2024C019-4)、商丘医学高等专科学校开放课题(KFKT23011)和2024河南省高等学校重点科研项目(24B350009)资助 |
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| 摘要点击次数: 59 |
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| 中文摘要: |
| 近年来在医药领域,纳米级药物载体正受到越来越多的关注,其独特的物理化学性质,如高表面积、可调控的尺寸和形状、多功能性等,使其在药物递送方面展现出显著优势。介绍了常见四种纳米级药物载体,包括脂质体、聚合物纳米颗粒、金属及其氧族化合物纳米颗粒和碳纳米材料等的制备方法,总结了纳米药物载体在癌症治疗、抗菌感染等领域的最新研究成果,展望了纳米药物载体的未来应用领域和发展趋势。 |
| 英文摘要: |
| In recent years, in the field of medicine, nanometer-scale drug carriers have been received increasing attention. Their unique physicochemical properties, such as high surface area, tunable size and shape, and multifunctionality, have demonstrated significant advantages in drug delivery. The preparation methods of four common types of nanometer-scale drug carriers are introduced, mainly including liposomes, polymer nanoparticles, metal or metal chalcogenide nanoparticles, and carbon nanomaterials. The latest research findings of nanometer drug carriers in the fields of cancer treatment and antibacterial infection are summarized, and the future application fields and development trends of nanometer drug carriers are prospected. |
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