王瑞环,贾伟娜,纪宽,闫雪峰.化学通报,2024,87(2):157-163. |
可注射水凝胶在伤口敷料中的研究进展 |
Research Progress in Injectable Hydrogels for Wound Dressings |
投稿时间:2023-07-25 修订日期:2023-08-29 |
DOI: |
中文关键词: 伤口敷料 天然材料 可注射水凝胶 抗菌活性 生物相容性 |
英文关键词:Wound dressing Natural material Injectable hydrogel Antibacterial activity Biocompatibility |
基金项目:国家重点研发计划项目(2019YFC0312101)资助 |
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中文摘要: |
目前,在伤口治疗中对伤口敷料的选择越来越严格。传统的伤口敷料如纱布、绷带、海绵等在伤口愈合过程中容易诱发细菌感染,延缓伤口愈合,甚至引发慢性并发症,。可注射水凝胶具备良好的生物相容性,能够适应伤口的形状以填充伤口,且具备一定的抗菌活性,从而避免伤口感染,相比传统的水凝胶伤口敷料更具备医疗优势,因此在生物医药领域得到广泛关注。本文对天然型可注射水凝胶和复合型可注射水凝胶在伤口愈合中的研究进展进行了综述;也对可注射水凝胶的未来发展趋势进行了展望。 |
英文摘要: |
At present, the choice of wound dressing in wound treatment is becoming more and more strict. Traditional wound dressings such as gauze, bandages, sponges, etc. are easy to induce bacterial infection during wound healing, delay wound healing, and even lead to chronic complications. Injectable hydrogels have good biocompatibility, can adapt to the shape of the wound to fill the wound, and have certain antibacterial activity, so as to avoid wound infection. Compared with traditional hydrogel wound dressings, they have more medical advantages, so they have been widely concerned in the field of biomedicine. The research progress of natural injectable hydrogels and compound injectable hydrogels in wound healing was reviewed in this paper. The future development trend of injectable hydrogels is also prospected. |
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